Gut-Brain Project

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Neuroticism is considered one of the “Big 5” personality traits, along with extraversion, agreeableness, conscientiousness and openness to experience. According to a

2009 article in the journal American Psychologist

, neuroticism refers to “tendencies to respond with negative emotions to threat, frustration, or loss.” In other words? Neurotics don’t exactly roll with the punches. And that can affect more than attitude and mood. In studies, neuroticism has been associated with negative health outcomes, including increased risk of mental conditions and physical health problems, as well as decreased occupational and marital satisfaction.

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From Wikipedia, the free encyclopediaNot to be confused with



Neuroticism (sometimes referred to as "emotional stability")is a higher-order personality trait in the study of psychology characterized by (susceptibility to) anxiety, fear, moodiness, worry, envy, frustration, jealousy, and loneliness.[1] Individuals who score high on neuroticism are more likely than average to experience such feelings as anxiety, anger, envy, guilt, and depressed mood.[2] People who are neurotic respond worse to stressors, are more likely to interpret ordinary situations as threatening, and minor frustrations as hopelessly difficult. They are often self-conscious and shy, and they may have trouble controlling urges and delaying gratification. High neuroticism indexes a risk constellation that exists prior to the development and onset of any of the "common mental disorders",[3][4] such as depression, phobia, panic disorder, other anxiety disorders, and substance use disorder—symptoms that traditionally have been called neuroses.[4][5][6][7][8]

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Health professionals no longer use the terms neurosis or neuroticism

As mentioned earlier, "neurosis" is not currently used by healthcare professionals. These days, neuroses-type references are placed under the areas of depressive disorders or anxiety. However, the term may still be used by some mental health professionals who still practice psychoanalysis.

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Anxiety and depression have been thought to contribute to gastro conditions like irritable bowel syndrome (IBS). A Johns Hopkins expert explains how what’s going on in your gut could be affecting your brain.

What the Experts DoCan Food Affect Your Mood?

Although there is a lot of folklore around this subject (particularly with spices such as pepper and curcumin or teas), there is really not enough rigorous science to make practical recommendations. A basic healthy diet is really important. Beyond that, listen to your gut. Your nervous system and gut may be wired to react to certain foods, and you may feel better if you avoid them. If you’ve ever come back after lunch and felt tired, nauseous, or a little “fuzzy,” your enteric nervous system may be reacting to something you ate—and sending signals to your brain.

If you’ve ever “gone with your gut” to make a decision or felt “butterflies in your stomach” when nervous, you’re likely getting signals from an unexpected source: your second brain. Hidden in the walls of the digestive system, this “brain in your gut” is revolutionizing medicine’s understanding of the links between digestion, mood, health and even the way you think.

Scientists call this little brain the enteric nervous system (ENS). And it’s not so little. The ENS is two thin layers of more than 100 million nerve cells lining your gastrointestinal tract from esophagus to rectum.

What Does Your Gut’s Brain Control?

Unlike the big brain in your skull, the ENS can’t balance your checkbook or compose a love note. “Its main role is controlling digestion, from swallowing to the release of enzymes that break down food to the control of blood flow that helps with nutrient absorption to elimination,” explains Jay Pasricha, M.D., director of the Johns Hopkins Center for Neurogastroenterology, whose research on the enteric nervous system has garnered international attention. “The enteric nervous system doesn’t seem capable of thought as we know it, but it communicates back and forth with our big brain—with profound results.”

The ENS may trigger big emotional shifts experienced by people coping with

irritable bowel syndrome (IBS)

and functional bowel problems such as




, bloating, pain and stomach upset. “For decades, researchers and doctors thought that anxiety and depression contributed to these problems. But our studies and others show that it may also be the other way around,” Pasricha says. Researchers are finding evidence that irritation in the gastrointestinal system may send signals to the central nervous system (CNS) that trigger mood changes

It is a text-book case and I am a writer, a scientific analyzer, and a fixer. What I've written could apply to anyone and many people in our modern culture, which is quite lacking in terms of how to be healthy. The older cultures didn't have much of this kind of problem with their emphasis on lots of cabbage, fermented vegetables, soured milks, beets, brewer's yeast, whole grains, etc. That's how they had a healthy gut and stable thinking, but those foods are not on the modern menu. Argentum Nitricum, if it applies, (search it on Amazon and see the customer reviews) and some other nutritional supplements are needed. By the way, Argentum is also for some physical symptoms such as: headache with coldness and trembling, pain, redness and discharge from eyes and eye strain, thick mucous and sensation of splinter or strangulation in throat, belching, swelling gastritis, colic with flatulent distension, diarrhea, female problems, respiratory problems and back pain, rigidity or debility in calves and unsteady walking, dry or blotched skin, chills with nausea. Worse warmth, at night, from emotion, sweats after eating, left side. Better from cold. It doesn't all have to fit you, but does any of this fit you. It would be no wonder that you wouldn't feel well with these conditions. But it is not hard to fix, if you fix the gut. Bad bacteria in the gut causes these problems. Argentum Nitricum is silver nitrate - but in homeopathy we use it in such highly diluted form that it is only the energy of silver in the medicine - and no side effects, perfectly safe. Bad bacteria can't live with silver, even the energy of silver kills them. And then you must replace with a good probiotic.

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The gut-brain axis (GBA) consists of bidirectional communication between the central and the enteric nervous system, linking emotional and cognitive centers of the brain with peripheral intestinal functions. Recent advances in research have described the importance of gut microbiota in influencing these interactions. This interaction between microbiota and GBA appears to be bidirectional, namely through signaling from gut-microbiota to brain and from brain to gut-microbiota by means of neural, endocrine, immune, and humoral links. In this review we summarize the available evidence supporting the existence of these interactions, as well as the possible pathophysiological mechanisms involved. Most of the data have been acquired using technical strategies consisting in germ-free animal models, probiotics, antibiotics, and infection studies. In clinical practice, evidence of microbiota-GBA interactions comes from the association of dysbiosis with central nervous disorders (i.e. autism, anxiety-depressive behaviors) and functional gastrointestinal disorders. In particular, irritable bowel syndrome can be considered an example of the disruption of these complex relationships, and a better understanding of these alterations might provide new targeted therapies.


Gut-brain axis, enteric microbiota, central nervous system, enteric nervous system, irritable bowel syndrome

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Insights into the gut-brain crosstalk have revealed a complex communication system that not only ensures the proper maintenance of gastrointestinal homeostasis, but is likely to have multiple effects on affect, motivation, and higher cognitive functions. The complexity of these interactions is enclosed in the denomination of “gut-brain axis” (GBA) [1]. Its role is to monitor and integrate gut functions as well as to link emotional and cognitive centers of the brain with peripheral intestinal functions and mechanisms such as immune activation, intestinal permeability, enteric reflex, and entero-endocrine signaling. The mechanisms underlying GBA communications involve neuro-immuno-endocrine mediators.

This bidirectional communication network includes the central nervous system (CNS), both brain and spinal cord, the autonomic nervous system (ANS), the enteric nervous system (ENS) and the hypothalamic pituitary adrenal (HPA) axis

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